Thermo Fisher Scientific YAF2 Polyclonal Antibody
YAF2 단백질을 인식하는 Rabbit Polyclonal 항체로 Western Blot 및 Immunocytochemistry에 적합. Human에 반응하며 Mouse에서 보고됨. 항원 친화 크로마토그래피로 정제된 액상 항체로, 1 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
- Publications: 1 publication available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to amino acids 1–180 of Human YAF2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2547833 |
Product Specific Information
- Recommended positive controls: 293T, Raji
- Predicted reactivity: Chicken (86%), Rhesus Monkey (86%), Bovine (86%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The YAF2 protein interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes.
YAF2 contains an N-terminal C2-X10-C2 zinc finger and is up-regulated during myogenic differentiation.
It facilitates proteolytic cleavage of YY1 by the calcium-activated protease m-calpain, suggesting a mechanism by which YAF2 antagonizes the negative effect of YY1.
⚠ WARNING
This product can expose you to chemicals including mercury, known to cause birth defects or other reproductive harm in the State of California.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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