Thermo Fisher Scientific ARHGAP22 Polyclonal Antibody

Thermo Fisher Scientific ARHGAP22 Polyclonal Antibody

Applications

• Western Blot (WB)

Tested Dilution: 1:500–1:1,000
Publications: [References not provided]

Product Specifications

Target Information

GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form.
ARHGAP22 (Rho GTPase activating protein 22), also known as RHOGAP2, is a 698 amino acid protein that localizes to the cytoplasm and contains one Rho-GAP domain and one PH domain.
ARHGAP22 functions as a GTPase-activating protein for Rac1, converting it to an inactive GDP-bound state. Through interaction with ZNF161 (VEZF1), it may be involved in transcription regulation. Multiple isoforms of ARHGAP22 exist due to alternative splicing events.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.