
Thermo Fisher Scientific ARHGAP22 Polyclonal Antibody
ARHGAP22 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 Rac1 GTPase 활성 조절 연구에 활용 가능. 고순도 액상 형태, -20°C 보관. 연구용 한정.
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Thermo Fisher Scientific ARHGAP22 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Publications: [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide derived from the internal region of human RHG22 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556005 |
Target Information
GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form.
ARHGAP22 (Rho GTPase activating protein 22), also known as RHOGAP2, is a 698 amino acid protein that localizes to the cytoplasm and contains one Rho-GAP domain and one PH domain.
ARHGAP22 functions as a GTPase-activating protein for Rac1, converting it to an inactive GDP-bound state. Through interaction with ZNF161 (VEZF1), it may be involved in transcription regulation. Multiple isoforms of ARHGAP22 exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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