Thermo Fisher Scientific ARHGEF1 Polyclonal Antibody
ARHGEF1 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal 항체입니다. Western blot 및 IHC(P) 등 다양한 응용에 적합하며, 고순도 액상 형태로 제공됩니다. 세포 신호전달 및 GTPase 연구용으로 사용됩니다.
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Thermo Fisher Scientific ARHGEF1 Polyclonal Antibody
Applications and Tested Dilutions
- Western Blot (WB): 1:500–1:1,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human ARHGEF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2556006 |
Target Information
The Ras superfamily of GTPases, which includes the Ras, Rho/Rac, Sar, Rab, ARF, and Ran subfamilies, regulates multiple cellular processes such as cytoskeletal rearrangement, nuclear signaling, and cell growth. These GTPases act as molecular switches toggling between active (GTP-bound) and inactive (GDP-bound) states. Guanine nucleotide exchange factors (GEFs) catalyze this activation.
Dbl-related proteins form a large family of structurally similar molecules that catalyze GEF activity for specific Ras family members, including FGD1, Lsc, RhoGEF p115, Lfc, Lbc, and Brx. Lsc, Lbc, and Lfc share sequence homology and exhibit exchange activity toward Rho family GTPases. RhoGEF p115 specifically catalyzes GEF activity for Rho but not Rac, Cdc42, or Ras GTPases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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