Thermo Fisher Scientific GRP75 Monoclonal Antibody (A6-A5-B1)
GRP75 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, 인간·마우스·랫트 시료에 반응합니다. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제된 액상 형태입니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgM |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A6-A5-B1 |
| Immunogen | Synthetic peptide within Human Grp75 aa 630–679 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA, 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931063 |
Target Information
The HSP70 family is composed of four highly conserved proteins: HSP70, HSC70, GRP75, and GRP78. These proteins serve various roles. GRP75 expression is restricted to the mitochondrial matrix and aids in the translocation and folding of nascent polypeptide chains from both nuclear and mitochondrial origins. GRP75 and GRP78 are unresponsive to heat stress and are induced by glucose deprivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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