
Thermo Fisher Scientific PSD-95 Monoclonal Antibody (B5-E6)
PSD-95 단백질을 인식하는 Thermo Fisher Scientific의 B5-E6 단클론 항체로, WB, IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 적합. 인간, 생쥐, 랫트에 반응하며, 항원 친화 크로마토그래피로 정제된 액상 형태. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | B5-E6 |
| Immunogen | Synthetic peptide within N-terminal human PSD95 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol, 0.2% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931065 |
Target Information
Post Synaptic Density 95 kDa (PSD-95), also known as synapse associated protein 90 kDa (SAP90), is a membrane-associated protein found in the postsynaptic density of forebrain neurons and certain presynaptic structures in the cerebellum. PSD-95 contains three PDZ domains, an SH3 domain, and a GuK domain, and is involved in clustering of NMDA receptors and Shaker-type potassium channels at the synaptic membrane. It interacts with proteins sharing the C-terminal T/SXV motif and can also associate with neuronal nitric oxide synthase (nNOS) through PDZ-PDZ interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(해당 항원 구조 이미지 및 PSD-95 관련 시각 자료)
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