Thermo Fisher Scientific Plexin-A1 Polyclonal Antibody
인간 Plexin-A1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 면역조직화학(IHC) 및 면역세포화학(ICC/IF)에 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 안정성 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- PA552444
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Plexin-A1 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PLXNA1. Recombinant protein control fragment (Product #RP-90138). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2645689 |
Product Specific Information
Immunogen sequence:
QDFNQPLGGT VTIEGTPLFV DKDDGLTAVA AYDYRGRTVV FAGTRSGRIR KILVDLSNPG GRPALAYESV VAQEGSPILR DLVLSPNHQY LYAMTEKQVT
Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 95%
Target Information
Coreceptor for SEMA3A, SEMA3C, SEMA3F, and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth, and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for activation of downstream signaling events in the cytoplasm. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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