Thermo Fisher Scientific ACCN4 Polyclonal Antibody
Western blot 및 IHC에 적합한 Rabbit Polyclonal 항체로, 인간, 마우스, 랫트 반응성을 가짐. ASIC4 단백질의 480-530 aa 영역 합성 펩타이드로 면역화됨. 동결건조 형태로 제공되며, 장기 보관 시 -20°C 권장. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 2 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 480–530 of human ASIC4 conjugated to an immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The antigen is homologous in rat and mouse.
- Specificity: ASIC4.
Target Information
This gene belongs to the superfamily of acid-sensing ion channels (ASICs), which are proton-gated, amiloride-sensitive sodium channels. These channels are involved in synaptic transmission, pain perception, and mechanoperception. The gene is predominantly expressed in the pituitary gland and was once considered a candidate for paroxysmal dystonic choreoathetosis (PDC), though no correlation was found between mutations and PDC. Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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