Thermo Fisher Scientific ACCN4 Polyclonal Antibody
ASIC4 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot 및 Immunohistochemistry에 사용 가능. 합성 펩타이드(aa 10-60)를 항원으로 제작. 동결건조 형태로 제공되며, 4°C 또는 -20°C에서 보관. 연구용으로만 사용 가능.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:300–1:2,000
- Immunohistochemistry (IHC): 1:300–1:2,000
- Miscellaneous PubMed (Misc): –
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 10–60 of human ASIC4 conjugated to immunogenic carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: ASIC4
Target Information
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception, and mechanoperception. The gene is predominantly expressed in the pituitary gland and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder; however, no correlation was found between mutations in this gene and PDC.
Alternative splicing at this locus results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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