Thermo Fisher Scientific GSTM3 Polyclonal Antibody
Thermo Fisher Scientific GSTM3 Polyclonal Antibody는 인간 GSTM3 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot 및 IHC(P)에서 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능하며, 장기 보관 시 -20°C에서 보관하십시오.
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Applications
Western Blot (WB)
- Tested Dilution: Not specified
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
- View publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GSTM3. Recombinant protein control fragment (Product # RP-95123) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642249 |
Product Specific Information
Immunogen sequence:
TYDILDQNRI FDPKCLDEFP NLKAFMCRFE ALEKIAAYLQ SDQFCKMPIN N
Highest antigen sequence identity to the following orthologs:
- Mouse: 90%
- Rat: 86%
Target Information
Glutathione S-transferase M3 (brain), also known as GSTM3, is an enzyme encoded by the GSTM3 gene in humans. This enzyme belongs to the mu class of glutathione S-transferases, which function in detoxification of electrophilic compounds such as carcinogens, therapeutic drugs, environmental toxins, and oxidative stress products through conjugation with glutathione.
The mu class genes are organized in a cluster on chromosome 1p13.3 and are highly polymorphic. These genetic variations can influence susceptibility to toxins and carcinogens, as well as drug efficacy and toxicity. Mutations in this gene have been associated with a slight increase in cancer risk due to environmental toxin exposure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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