Thermo Fisher Scientific THADA Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human THADA. Recombinant protein control fragment (Product #RP-102654). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:THADA,uniProtId:Q6YHU6-1,ncbiNodeId:9606,antigenRange:1066-1159,antigenLength:1953,antigenImageFileName:PA5-57193_THADA_Q6YHU6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57193_THADA_Q6YHU6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648423

Product Specific Information

Immunogen sequence: MLCQLLPMQP VPESSDGLLT VEQVKEIGDY FKQHLLQSRH RGAFELAYTG FVKLTEVLNR CPNVSLQKLP EQWLWSVLEE IKCSDPSSKL CATR

Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 90%.

Target Information

THADA (thyroid adenoma associated), also known as GITA, is a 1,953 amino acid protein that is expressed in testis, thyroid, pancreas, stomach and small intestine. Chromosomal aberrations in the gene encoding THADA are associated with benign thyroid adenomas, suggesting a potential role for THADA in tumorigenesis. The THADA gene maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the chromosome 2-localized ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes, which also map to chromosome 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.