Thermo Fisher Scientific Human Enterokinase, Animal-Free Recombinant Protein, PeproTech
CHO 세포에서 발현된 동물 유래 성분 없는 재조합 인간 Enterokinase 단백질. 트립시노겐을 트립신으로 전환하는 효소로 기능하며, 고순도(≥90%) 및 낮은 엔도톡신(<0.2 EU/µg)을 특징으로 함. 기능적 단백질 활성 검증 완료, 연구용으로 적합.
- 카탈로그번호
- AF-450-48C-xxx (5개 옵션)
- 카테고리
- Enzymes
- 판매단위
- pk
카탈로그
5개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human Enterokinase, Animal-Free Recombinant Protein, PeproTech
Applications
- Functional Assay (Functional)
Tested Dilution: Assay-dependent
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | CHO cells |
| Amino Acid Sequence | Heavy chain and Light chain (see below) |
| Molecular Weight | 108.7 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 90% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | <0.2 EU/µg |
| Activity | Sequentially cleaves carboxyl side of D-D-D-D-K |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Amino Acid Sequence
Heavy Chain:
LTIKESQRGA ALGQSHEARA TFKITSGVTY NPNLQDKLSV DFKVLAFDLQ QMIDEIFLSS NLKNEYKNSR VLQFENGSII VVFDLFFAQW VSDQNVKEEL IQGLEANKSS QLVTFHIDLN SVDILDKLTT TSHLATPGNV SIECLPGSSP CTDALTCIKA DLFCDGEVNC PDGSDEDNKM CATVCDGRFL LTGSSGSFQA THYPKPSETS VVCQWIIRVN QGLSIKLSFD DFNTYYTDIL DIYEGVGSSK ILRASIWETN PGTIRIFSNQ VTATFLIESD ESDYVGFNAT YTAFNSSELN NYEKINCNFE DGFCFWVQDL NDDNEWERIQ GSTFSPFTGP NFDHTFGNAS GFYISTPTGP GGRQERVGLL SLPLDPTLEP ACLSFWYHMY GENVHKLSIN ISNDQNMEKT VFQKEGNYGD NWNYGQVTLN ETVKFKVAFN AFKNKILSDI ALDDISLTYG ICNGSLYPEP TLVPTPPPEL PTDCGGPFEL WEPNTTFSST NFPNSYPNLA FCVWILNAQK GKNIQLHFQE FDLENINDVV EIRDGEEADS LLLAVYTGPG PVKDVFSTTN RMTVLLITND VLARGGFKAN FTTGYHLGIPEPCKADHFQC KNGECVPLVN LCDGHLHCED GSDEADCVRF FNGTTNNNGL VRFRIQSIWH TACAENWTTQ ISNDVCQLLG LGSGNSSKPI FSTDGGPFVK LNTAPDGHLI LTPSQQCLQD SLIRLQCNHK SCGKKLAAQD ITPK
Light Chain:
IVGGSNAKEG AWPWVVGLYY GGRLLCGASL VSSDWLVSAA HCVYGRNLEP SKWTAILGLH MKSNLTSPQT VPRLIDEIVI NPHYNRRRKD NDIAMMHLEF KVNYTDYIQP ICLPEENQVF PPGRNCSIAG WGTVVYQGTT ANILQEADVP LLSNERCQQQ MPEYNITENM ICAGYEEGGI DSCQGDSGGP LMCQENNRWF LAGVTSFGYK CALPNRPGVY ARVSRFTEWI QSFLH
Product Specific Information
Human Enterokinase is expressed as a linear 1019 amino acid precursor glycoprotein. Proteolytic processing generates the biologically active heterodimer composed of a heavy chain (784 amino acids) and a light chain (235 amino acids) linked by a disulfide bond. The calculated molecular weight is 108.7 kDa.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please refer to the lot-specific Certificate of Analysis.
Target Information
This gene encodes an enzyme that converts pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains forming a heterodimer linked by a disulfide bond. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive.
(Information provided by RefSeq, Jul 2008)
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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