Thermo Fisher Scientific GPR120/FFAR4 (extracellular) Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Reconstitution: Add 25 µL, 50 µL, or 0.2 mL of double-distilled water (DDW), depending on the sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
The reconstituted solution can be stored at 4°C for up to 1 week. For longer-term storage, aliquot and store at -20°C.
Avoid repeated freeze/thaw cycles. Centrifuge antibody preparations before use (10,000 × g, 5 min).

Target Information

An EST for GPR120 has been isolated from a human colon cancer library.
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules, with more than a thousand members predicted.
All GPCRs share a structural motif of seven membrane-spanning helices and exist in both active and inactive forms.
Activating ligands induce conformational changes leading to signaling via G-proteins and downstream effectors.
Negative regulation of GPCRs also plays a crucial role in cellular physiology and pharmacology, inspiring the development of GPCR-targeted drugs such as Zyprexa and Claritin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.