Thermo Fisher Scientific CYP1A2 Monoclonal Antibody (OTI7D12), TrueMAB
인간 CYP1A2 단백질을 인식하는 mouse monoclonal antibody. ELISA에 적합하며, 약물 대사 관련 연구에 활용 가능. Affinity chromatography로 정제된 액상 형태로 제공. -20°C 보관, 반복 동결·해동은 피해야 함.
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Applications
- ELISA (ELISA)
Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7D12 |
| Immunogen | Full-length human recombinant protein of CYP1A2 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with <5% trehalose |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by certain polycyclic aromatic hydrocarbons (PAHs), including those found in cigarette smoke.
Although the enzyme’s endogenous substrate is unknown, it can metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates include caffeine, aflatoxin B1, and acetaminophen.
The transcript contains four Alu sequences flanked by direct repeats in the 3′ untranslated region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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