Thermo Fisher Scientific CYP1A2 Monoclonal Antibody (OTI7A9), TrueMAB
인간 CYP1A2 단백질을 인식하는 Mouse IgG1 단일클론 항체로 ELISA에 적합. Affinity chromatography로 정제된 액상형 제품. 약물 대사 관련 연구용으로 사용. -20°C 보관, 동결·해동 반복 방지 필요.
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Applications
- ELISA (ELISA)
Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7A9 |
| Immunogen | Full length human recombinant protein of human CYP1A2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with <5% trehalose |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke.
The enzyme’s endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen.
The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3′ untranslated region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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