Thermo Fisher Scientific EML1 Polyclonal Antibody

Applications

• Western Blot (WB)
  Tested dilution: 1:500–1:3,000
  View 1 publication

Product Specifications

Product Specific Information

• Recommended positive controls: A549, HeLa, HepG2, mouse brain
• Predicted reactivity: Mouse (93%), Rat (93%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Human echinoderm microtubule-associated protein-like (EML1) is a strong candidate for the Usher syndrome type 1A gene.
Usher syndromes (USHs) are a group of genetic disorders consisting of congenital deafness, retinitis pigmentosa, and vestibular dysfunction of variable onset and severity depending on the genetic type.
USHs are categorized as:

• Type I (USH1A–USH1F)
• Type II (USH2A, USH2B)
• Type III (USH3)

Type I is the most severe form. Gene loci responsible for these three types are all mapped. Two transcript variants encoding different isoforms have been found for this gene.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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