Thermo Fisher Scientific SEMA6D Polyclonal Antibody

Applications

• Western Blot (WB): 1:1,000–1:3,000

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total SEMA6D.

Target Information

Semaphorins are a large family of secreted and membrane-associated proteins involved in axon pathfinding, fasciculation, branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins, and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Transmembrane semaphorins, like secreted ones, can act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin with multiple alternatively spliced transcript variants, whose expression is regulated in a tissue- and development-dependent manner.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.