Thermo Fisher Scientific Relaxin 3 Polyclonal Antibody
Thermo Fisher Scientific의 Relaxin 3 Polyclonal Antibody는 인간 RLN3 단백질을 인식하는 토끼 IgG 항체입니다. Western blot 및 ICC/IF에 사용 가능하며, 고순도 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
- 카탈로그번호
- PA599868
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RLN3 (Accession Q8WXF3), corresponding to amino acid residues R104–C142 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818801 |
Product Specific Information
Antibody detects endogenous levels of total RLN3.
Target Information
Relaxin 3 is part of the Relaxin-like peptide family that plays an important neuropeptide signaling role. It acts as a ligand for human Relaxin receptor 3 and Relaxin receptor 4.
The highest expression levels are found in the brain—particularly in the pons/medulla and dorsal tegmental nucleus—with lower levels in the hippocampus and olfactory regions.
Significant expression also occurs in the spleen, thymus, lung, and ovary. Relaxin 3 inhibits Forskolin-stimulated cAMP accumulation in cells expressing Relaxin receptor 3.
Administration of Relaxin 3 decreases plasma thyroid stimulating hormone levels, suggesting a role in long-term regulation of food intake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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