Thermo Fisher Scientific SALL4 Monoclonal Antibody (6E3)
SALL4 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Human 및 Mouse 시료에 반응합니다. Western blot, IHC, ELISA에 사용 가능하며, 줄기세포 및 종양 바이오마커 연구용으로 적합합니다. -20°C 보관, PBS 버퍼 기반의 액상 제품입니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-Dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.2 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6E3 |
| Immunogen | SALL4 (NP_065169, 954–1053 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
PKEILAPSVN VDPVVWNQYT SMLNGGLAVK TNEISVIQSG GVPTLPVSLG ATSVVNNATV SKMDGSQSGI SADVEKPSAT DGVPKHQFPH FLEENKIAVS
Target Information
Sall4 protein is encoded by the Sall4 gene located on chromosome 20 in humans and belongs to the Spalt-like protein family. It plays an important role in somatic stem cell maintenance and is studied as a stem cell biomarker. It is a zinc finger transcription factor that is upregulated during development and shown to interact with Oct4 and Sox2. It also forms a complex with Nanog to maintain the pluripotency of embryonic stem cells (ESCs).
Several research studies focus on its function as an oncogene and tumor biomarker. Reported target genes of Sall4 include p53, Bmi-1, Bcl2, and XIAP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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