Thermo Fisher Scientific SALL4 Monoclonal Antibody (6E3)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-Dependent

-

Immunohistochemistry (Paraffin) (IHC (P))

0.2 µg/mL

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

6E3

Immunogen

SALL4 (NP_065169, 954 a.a. approximately 1053 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SALL4,uniProtId:Q9UJQ4-1,ncbiNodeId:9606,antigenRange:954-1053,antigenLength:1053,antigenImageFileName:H00057167-M03J_SALL4_Q9UJQ4-1_House_mouse.svg,antigenImageFileNamePDP:H00057167-M03J_SALL4_Q9UJQ4-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: PKEILAPSVN VDPVVWNQYT SMLNGGLAVK TNEISVIQSG GVPTLPVSLG ATSVVNNATV SKMDGSQSGI SADVEKPSAT DGVPKHQFPH FLEENKIAVS

Target Information

Sall4 protein is encoded by the Sall4 gene located on chromosome 20 in humans and belongs to the Spalt-like protein family. It plays an important role in somatic stem cell maintenance and is studied as a stem cell biomarker. It is a zinc finger transcription factor that is upregulated during development and shown to interact with Oct4 and Sox2. It also forms a complex with Nanog to maintain the pluripotency of Embryonic Stem cells (ESCs). Several current research studies focus on its function as an oncogene and tumor biomarker. Some of the reported target genes of Sall4 include p53, Bmi-1, Bcl2 and XIAP.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.