Thermo Fisher Scientific C8orf4 Polyclonal Antibody
C8orf4 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 인간 시료에 반응하며 Wnt/β-catenin 신호전달 연구에 유용합니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal region of human C8orf4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691034 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%
Target Information
This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/β-catenin signaling pathway. It interacts with a repressor of β-catenin mediated transcription at nuclear speckles, competitively blocking the repressor’s interactions with β-catenin and leading to up-regulation of β-catenin target genes.
The encoded protein may also play roles in NF-κB and ERK1/2 signaling pathways. Expression of this gene has been associated with proliferation in several cancers, including thyroid, breast, and hematological malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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