Thermo Fisher Scientific TRPV2 Polyclonal Antibody
Thermo Fisher Scientific의 TRPV2 Polyclonal Antibody는 인간 TRPV2 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot 및 IHC(P)에서 검증되었으며, 고온 활성화 이온 채널 연구에 적합합니다. 동결건조 형태로 제공되며 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 | - |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human TRPV2 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_962458 |
Product Specific Information
- Glycerol (1:1) may be added for additional stability.
- Reconstitute with 100 µL of sterile water.
Target Information
VLR-1 (TRPV2) is a calcium-permeable, non-selective cation channel with outward rectification. It is regulated by growth factors such as IGF1, PDGF, and morphogenetic neuropeptides.
VRL-1 does not respond to capsaicin, acid, or moderate heat, but is activated by high temperatures (~52°C).
In sensory ganglia, VRL-1 is expressed in medium- to large-diameter neurons, suggesting its role in high-threshold heat response.
VRL-1 transcripts are also found outside the sensory nervous system, indicating activation by stimuli other than heat.
VRL-1 is one of six members of the vanilloid-like TRP-channel family, now known as the TRPV family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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