Thermo Fisher Scientific Histone H2B Polyclonal Antibody
다종 간 보존된 히스톤 H2B를 인식하는 Rabbit Polyclonal 항체로, WB, IHC(P), ChIP 등 다양한 응용에 적합. 고순도 Protein G 정제, 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | References |
|---|---|---|
| Western Blot (WB) | 2 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 10 µg/mL | - |
| ChIP assay (ChIP) | 1.5 µg per million cells | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Chicken, Fruit fly, Human, Mammal, Mouse, Rat, Zebrafish |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 111–125 of human histone H2B [GenBank no. CAI19747.1] |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2118162 |
Product Specific Information
- The peptide sequence is 100% conserved among multiple species including human, mouse, rat, dog, chimpanzee, cow, chicken, duck, zebrafish, and drosophila.
- Suggested positive control: Jurkat, PBMC.
Target Information
Histones are basic nuclear proteins responsible for the nucleosome structure of chromosomal fibers in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of the four core histones (H2A, H2B, H3, and H4).
These structures compact DNA into chromatin, regulating DNA accessibility for transcription, repair, replication, and chromosomal stability.
Histone H2B also exhibits broad antibacterial activity.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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