Thermo Fisher Scientific CCR1 Polyclonal Antibody
CCR1 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot, IHC, ICC/IF, Flow Cytometry 등 다양한 응용에 사용 가능합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS 완충액에 보존됩니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–3 µg/mL | View 4 publications |
| Immunohistochemistry (IHC) | – | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL | – |
| Immunocytochemistry (ICC/IF) | Assay-Dependent | View 1 publication |
| Flow Cytometry (Flow) | 5–10 µL/test | View 2 publications |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to human CCR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2074018 |
Product Specific Information
Suggested positive control: A375, antigen standard for CCR1 (transient overexpression lysate).
Target Information
Chemokines play important roles in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The chemokine receptor subtypes can be divided into two major groups, CXCR and CCR, based on the two major classes of chemokines.
CCR1, one of the CCR receptors, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils. It binds to macrophage-inflammatory protein (MIP-1), eotaxin, and other related chemokines. Mice lacking CCR1 show defects in neutrophil trafficking and proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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