Thermo Fisher Scientific eIF6 Monoclonal Antibody (A6A3)
Western blot과 IHC(P)에서 검증된 eIF6 단클론 항체로, Human, Mouse, Rat에 반응합니다. 단클론 IgG2a 형식이며, Protein G로 정제된 액상 형태입니다. 세포질 및 핵소체에서의 eIF6 단백질 검출에 적합합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A6A3 |
| Immunogen | Recombinant protein within human eIF-6 (aa 1–200) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2911689 |
Product Specific Information
- Positive Control: Hela cell lysate, CRC cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, human esophagus tissue, human ovarian carcinoma tissue, mouse colon tissue
- Subcellular Location: Nucleolus, Cytoplasm
Target Information
Hemidesmosomes are structures linking the basal lamina to the intermediate filament cytoskeleton. An important functional component is the integrin beta-4 subunit (ITGB4), which contains two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, found both in the nucleus and cytoplasm, functions as a translation initiation factor and prevents association of the 40S and 60S ribosomal subunits. Multiple transcript variants encoding two different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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