Thermo Fisher Scientific CD52 (Epididymis-Specific Protein 5) Recombinant Rabbit Monoclonal Antibody (CD52, 2276R)
인간 및 비인간 영장류 반응성을 가진 재조합 토끼 단일클론 항체. IHC(P)에서 1–2 µg/mL로 사용 가능. CD52 단백질을 면역원으로 하여 제작된 비결합형 액상 항체로, 면역세포 표면 단백질 연구에 적합. 연구용으로만 사용 가능.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | CD52, 2276R |
| Immunogen | Recombinant full-length human CD52 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature (RT).
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at RT for 20 min.
Target Information
CD52, also known as CAMPATH-1 antigen, is a glycoprotein expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes.
It plays a role in immune response regulation and is studied as a therapeutic target in multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders.
CD52 is the target of alemtuzumab, a monoclonal antibody used to treat these conditions by depleting CD52-expressing immune cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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