Thermo Fisher Scientific CD52 (Epididymis-Specific Protein 5) Recombinant Rabbit Monoclonal Antibody (CD52, 2276R)
CD52 단백질을 인식하는 Thermo Fisher Scientific의 재조합 토끼 단클론 항체입니다. 인간 및 비인간 영장류 반응성을 가지며, IHC(P) 실험에 적합합니다. 단백질 A/G로 정제된 액상 형태로 제공되며, 보존제가 없습니다. 연구용으로만 사용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host/Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | CD52, 2276R |
| Immunogen | Recombinant full-length human CD52 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 min.
Target Information
CD52, also known as CAMPATH-1 antigen, is a glycoprotein expressed on the surface of various immune cells, including T and B lymphocytes, natural killer cells, and monocytes.
It plays a role in immune regulation and is a therapeutic target in diseases such as multiple sclerosis, chronic lymphocytic leukemia, and autoimmune disorders.
CD52 is the target of alemtuzumab, a monoclonal antibody used to deplete CD52-expressing immune cells in these conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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