Thermo Fisher Scientific GTF2B Monoclonal Antibody (OTI2F5), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

Ubiquitin is a 76-amino-acid, highly conserved eukaryotic polypeptide that marks cellular proteins for proteolytic degradation by the 26S proteasome. This posttranslational modification regulates the concentrations of key regulatory proteins by controlling their degradation.
Polyubiquitination involves activation (E1), conjugation (E2), and ligation (E3) enzymes, with deubiquitination enzymes reversing the process.
Ubiquitin tagging is essential in processes such as cell cycle regulation, differentiation, apoptosis, DNA repair, transcription regulation, signal transduction, and immune responses.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.