Thermo Fisher Scientific GTF2B Monoclonal Antibody (OTI2F5), TrueMAB
GTF2B 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합합니다. Human, Mouse, Rat에 반응하며, Lyophilized 형태로 제공됩니다. PBS 버퍼에 8% trehalose를 포함하고, -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 43–316 of human GTF2B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Ubiquitin is a 76-amino-acid, highly conserved eukaryotic polypeptide that marks cellular proteins for proteolytic degradation by the 26S proteasome. This posttranslational modification regulates the concentrations of key regulatory proteins by controlling their degradation.
Polyubiquitination involves activation (E1), conjugation (E2), and ligation (E3) enzymes, with deubiquitination enzymes reversing the process.
Ubiquitin tagging is essential in processes such as cell cycle regulation, differentiation, apoptosis, DNA repair, transcription regulation, signal transduction, and immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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