Thermo Fisher Scientific NFX1 Polyclonal Antibody
Human NFX1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC에 적합. 합성 펩타이드 면역원 사용으로 높은 특이성과 재현성 제공. 액상 형태, 0.5 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.2–1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human NFX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2607980 |
Product Specific Information
- Peptide sequence:
TLTGVLEREM QARPPPPIPH HRHQSDKNPG SSNLQKITKE PIIDYFDVQD - Sequence homology:
Cow: 85%; Dog: 85%; Human: 100%; Mouse: 76%; Rabbit: 85%; Rat: 85%
Target Information
MHC class II gene expression is primarily controlled at the transcriptional level by transcription factors that bind to the X and Y boxes, two conserved elements in the proximal promoter of MHC class II genes.
NFX1 is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro.
The protein may regulate the duration of inflammatory responses by limiting the period in which class II MHC molecules are induced by IFN-gamma.
Three alternative splice variants have been identified, each encoding a different isoform.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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