Thermo Fisher Scientific LECT1 Polyclonal Antibody
LECT1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human LECT1, amino acids 231–334 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ChM-1 is a cartilage-specific matrix glycoprotein that stimulates the growth of chondrocytes. It inhibits angiogenesis by disrupting endothelial tube formation, contributing to the avascular nature of cartilage. ChM-1 is highly expressed in the proliferating and hypertrophic zones of the epiphyseal plate in long bones and accumulates in the interterritorial matrix around lacunae. During development, downregulation of ChM-1 allows angiogenesis and bone formation. Its expression is reduced by growth factors such as TGFβ2, FGF2, and PTHLH. ChM-1 may also be involved in the hypovascularity and chondroid formation of pleomorphic adenomas. The human gene encoding ChM-1 maps to chromosome 13q14–q21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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