Thermo Fisher Scientific Phospho-CDC37 (Ser13) Recombinant Rabbit Monoclonal Antibody (23GB3595)
Phospho-CDC37 (Ser13)을 인식하는 재조합 토끼 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 적합합니다. Human, Mouse, Rat 반응성을 가지며, HEK293F 발현 시스템에서 생산되었습니다. -20°C 보관, 연구용 전용입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:5,000 |
| Immunocytochemistry (ICC/IF) | 1:1,000 |
| Flow Cytometry (Flow) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB3595 |
| Immunogen | A synthetic peptide of human Phospho-CDC37 (Ser13) (6–20AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
In S. cerevisiae, Cdc37 has been shown to be an important regulator of the cell division cycle through its action on cyclin-dependent kinases (CDKs). Cdc37 is also associated with signaling pathways and kinases unrelated to cell cycle control, including v-Src, casein kinase II, MPS1 kinase, and the sevenless receptor tyrosine kinase. HSP90 has been shown to associate with many of the same cellular targets as Cdc37. Cdc37 (also known as p50) interacts with Src-family kinases (Fyn, Yes, Fes, Lck, Fgr), Raf, and pp60v-src, functioning as a chaperone independently and in conjunction with HSP90. Cdc37 is required for HSP90 binding to Cdk4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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