Thermo Fisher Scientific MALT1 Recombinant Mouse Monoclonal Antibody (rMT1, 410)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1–2 µg/mL

Product Specifications

Product Specific Information

• Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
• Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.

Target Information

MALT1 (Paracaspase) was identified as a member of the human paracaspase family and an interacting partner of B-cell lymphoma (Uren et al., 2000).
MALT1 is a caspase-like protein containing an N-terminal death domain, two Ig-like domains, and a C-terminal caspase-like domain. It binds to Bcl10 through its Ig-like domains and cooperates with Bcl10 to activate NF-kappaB.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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