Thermo Fisher Scientific CYPIB1 Polyclonal Antibody
CYP1B1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot과 IHC에 사용 가능하며, 인간 및 영장류 시료에 반응. 동결건조 형태로 제공되며, 장기 보관 시 -20°C에서 보관 권장. 연구용 한정.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:5,000 |
| Immunohistochemistry (IHC) | 1:5,000 |
| Miscellaneous PubMed (Misc) | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human CYPIB1 conjugated to blue carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: CYP1B1
Target Information
CYP1B1 is a 543 amino acid intracellular protein localized to the endoplasmic reticulum. It belongs to the cytochrome P450 superfamily of enzymes (monooxygenases) that catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
This enzyme metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17β-estradiol, and is also involved in metabolism of substances active in eye growth and differentiation, suggesting a role in ocular development.
Mutations in this protein are known to cause primary congenital glaucoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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