Thermo Fisher Scientific VNN1 Monoclonal Antibody (C2)
VNN1 단백질을 인식하는 Mouse monoclonal antibody (Clone C2). Western blot, IHC(P), ICC/IF에 적합. Human 및 Pig 시료에 반응. Protein A/G로 정제된 액상 항체로, 장기 보관 시 -20°C 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.01–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–20 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–20 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C2 |
| Immunogen | Recombinant Human VNN1 protein, Gln22–Gly491 (Accession #O95497) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.05% Proclin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3093339 |
Target Information
Hematopoietic precursor cells migrate to the thymus, where they differentiate into mature T lymphocytes. The GPI-anchored vanin-1 protein regulates the late adhesion steps of thymus homing of bone marrow precursor cells. Vanin-1 acts as a pantetheinase enzyme, catalyzing the hydrolysis of pantetheine for vitamin B5 recycling and generating cysteamine, a potent antioxidant. As a membrane-bound pantetheinase, vanin-1 provides the main source of cysteamine under normal physiological conditions. In mice, vanin-1 is expressed specifically in male Sertoli cells of the developing testis, aiding in cell migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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