Thermo Fisher Scientific CXCR2 Monoclonal Antibody (C8)

Applications

Tested Dilution

Publications

Western Blot (WB)

0.01-2 µg/mL

-

Product Specifications

Species Reactivity

Human, Pig

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

C8

Immunogen

Recombinant Human IL8Rb protein, Met1-Leu57 (Accession #P25025) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CXCR2,uniProtId:P25025-1,ncbiNodeId:9606,antigenRange:1-57,antigenLength:360,antigenImageFileName:MA5-51155_CXCR2_P25025-1_House_mouse.svg,antigenImageFileNamePDP:MA5-51155_CXCR2_P25025-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A/G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.05% Proclin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3090557

Target Information

CXCR2 is a receptor for interleukin-8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to GRO/MGSA and NAP-2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.