
Thermo Fisher Scientific Supt4h1 Polyclonal Antibody
SUPT4H1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 최적화되어 있음. Human, Mouse, Rat에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관하며 연구용으로 사용.
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Applications
- Western Blot (WB): 1:500–1:1,000 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human SUPT4H1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719422 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
SUPT4H1 is a component of the DRB sensitivity-inducing factor (DSIF) complex, which regulates mRNA processing and transcription elongation by RNA polymerase II.
- DSIF positively regulates mRNA capping by stimulating RNGTT/CAP1A activity.
- Cooperates with the NELF complex to enhance transcriptional pausing near promoters.
- Promotes assembly of elongation-competent RNA polymerase II complexes.
- Suppresses transcriptional pausing and premature release of HIV-1 transcripts, facilitating efficient elongation by Tat.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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