Thermo Fisher Scientific MT-ND4L Polyclonal Antibody
Rabbit polyclonal antibody against human MT-ND4L, suitable for ICC/IF. Affinity-purified and supplied in PBS with glycerol. Detects mitochondrial NADH dehydrogenase subunit 4L, useful for mitochondrial research. For research use only.
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Applications
Immunocytochemistry (ICC/IF)
- Tested dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human MT-ND4L. Recombinant protein control fragment (Product #RP-108057) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2662362 |
Product Specific Information
- Immunogen sequence: LLVSISNTYGL DYVHNLNLLQ
- Sequence identity: Highest antigen sequence identity to mouse (81%) and rat (86%).
Target Information
NADH:ubiquinone oxidoreductase (complex I) is a multiprotein complex located in the inner mitochondrial membrane. It plays a key role in energy metabolism by transferring electrons from NADH to ubiquinone, coupled with proton translocation across the mitochondrial membrane.
Human complex I consists of 41 subunits, with subunits 1–7 encoded by mitochondrial genes and the rest by nuclear genes. NADH dehydrogenase subunit 4L (ND4L) is a component of the hydrophobic protein fragment of Complex I. Mutations in the ND4 gene are associated with Leber hereditary optic neuropathy, which can cause loss of central vision.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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