Thermo Fisher Scientific Phospho-RUNX1 (Ser249) Polyclonal Antibody
RUNX1 단백질의 Ser249 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 사용 가능. Human, Mouse, Rat 등 다종 반응성. 고순도 정제 및 안정적 PBS/glycerol buffer 제공.
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- PA5104570
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카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: References
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RUNX1 (Accession Q01196), corresponding to amino acid residues around phosphorylated Ser249 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816045 |
Product Specific Information
This antibody detects endogenous levels of RUNX1 / AML1 only when phosphorylated at Ser249.
Target Information
RUNX1 belongs to the mammalian RUNX family of DNA-binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression. It is essential for hematopoietic stem cell generation in the vascular regions of the aorta, vitelline and umbilical arteries, yolk sac, and placenta. RUNX1 is expressed in all tissues except brain and heart, with highest levels in thymus, bone marrow, and peripheral blood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일명: PA5-104570_RUNX1_Q01196-1_Rabbit.svg, PA5-104570_RUNX1_Q01196-1_Rabbit_PDP.jpeg)
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