Thermo Fisher Scientific PRR14 Polyclonal Antibody
PRR14 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며 IHC 및 IHC(P) 응용에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- PA563828
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: -
- View 1 publication
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:1,000–1:2,500
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PRR14 (UniProt ID: Q9BWN1-1, antigen range: 120–223) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645985 |
Product Specific Information
Immunogen sequence:
IHRTSSTLRR RSRTTPGPEE GPSQKVDRAP QPTLVVMLED IASPRPPAEG FIDETPNFII PAQRAEPMRI VRQPTPPPGD LEPPFQPSAL PADPLESPPT APDP
Sequence identity:
- Mouse: 49%
- Rat: 49%
Target Information
The protein encoded by PRR14 tethers heterochromatin to the nuclear laminar scaffold by binding heterochromatin protein 1 (HP1) and the nuclear lamina.
This tether is broken during mitosis and reforms quickly after mitosis, first binding HP1 and then attaching to the nuclear lamina.
The protein also promotes MyoD activity and skeletal myogenesis.
Two transcript variants encoding the same protein have been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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