Thermo Fisher Scientific SIGLEC11 Polyclonal Antibody
인간 SIGLEC11 단백질에 특이적인 Rabbit Polyclonal Antibody. IHC(P)에서 1:200–1:500 희석으로 검증됨. 항원 친화 크로마토그래피로 정제된 액상형 항체. PBS 버퍼 및 글리세롤 함유, 연구용으로 적합.
- 카탈로그번호
- PA563831
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific SIGLEC11 Polyclonal Antibody
Thermo Fisher Scientific SIGLEC11 Polyclonal Antibody
Applications
- Immunohistochemistry (Paraffin) [IHC (P)]: Tested dilution 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SIGLEC11 (UniProt ID: Q96RL6-1, antigen range: 668–698) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS (pH 7.2) with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2647301 |
Product Specific Information
- Immunogen sequence: YSEIKIHTGQ PLRGPGFGLQ LEREMSGMVP K
- Antigen sequence identity: Mouse - 37%, Rat - 35%
Target Information
Siglecs are sialic acid-binding lectins of the immunoglobulin superfamily, mainly expressed in hematopoietic cells.
Siglec11 specifically binds to α2-8-linked sialic acids and is expressed on macrophages rather than peripheral blood leukocytes.
It shares high homology with Siglec10 in the extracellular domain but differs in the cytoplasmic domain, suggesting gene duplication and recombination events.
Upon pervanadate treatment, Siglec11 becomes tyrosine-phosphorylated and associates with SHP-1 and SHP-2.
At least five isoforms of Siglec11 are known.
Usage
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.