Thermo Fisher Scientific IFITM3 Polyclonal Antibody
IFITM3 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ELISA, IP 등 다양한 응용에 적합합니다. 인공 합성 펩타이드(1-50 aa)로 면역화되었으며, Human 및 비인간 영장류에 반응합니다. 친화 크로마토그래피로 정제된 액상 항체입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 1–50 on human Interferon-induced transmembrane protein 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
IFITM3 (Interferon Induced Transmembrane Protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein belonging to the IFITM family. These proteins are induced by type I and II interferons and contain multiple interferon-stimulated response elements (ISREs) in their promoter regions. IFITM proteins play critical roles in cellular anti-proliferative activities, homotypic cell adhesion, and may contribute to carcinogenesis through their upregulation in cancer cells. IFITM3, a 133 amino acid membrane protein, is induced by IFN-α and IFN-γ, and its expression is regulated by TEF-1, Brg-1, and Sp1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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