Thermo Fisher Scientific IFI6 Polyclonal Antibody
Human IFI6 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ELISA, IP 등 다양한 응용에 적합. 합성 펩타이드(aa 80-130)로 면역화되었으며, 액상 형태로 제공. 고순도 친화 크로마토그래피 정제 및 -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 80–130 on human Interferon alpha-inducible protein 6 (IFI6) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
G1P3, also known as Interferon alpha-inducible protein 6 (IFI6) and Interferon-induced protein 6-16, is a 130 amino acid member of the IFI6 family of proteins. Localized to the mitochondria, G1P3 is a multi-pass membrane protein induced by IFN-α2β. It plays a major role in the apoptosis pathway by inhibiting caspase-3 activity, thereby acting as a cell survival protein. G1P3 has been implicated in tumorigenesis and is under investigation as a potential therapeutic target, as reducing G1P3-mediated antiapoptotic signaling may improve treatments for myeloma and other malignancies.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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