Thermo Fisher Scientific CD162 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 20-149. Recombinant protein control fragment (Product #RP-110195). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD162 (PSGL-1),uniProtId:Q14242-1,ncbiNodeId:9606,antigenRange:20-149,antigenLength:412,antigenImageFileName:PA5-144701_CD162_PSGL-1_Q14242-1_Rabbit.svg,antigenImageFileNamePDP:PA5-144701_CD162_PSGL-1_Q14242-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3091741

Product Specific Information

Immunogen sequence: LWDTWADEAE KALGPLLARD RRQATEYEYL DYDFLPETEP PEMLRNSTDT TPLTGPGTPE STTVEPAARR STGLDAGGAV TELTTELANM GNLSTDSAAM EIQTTQPAAT EAQTTQPVPT EAQTTPLAAT

Antigen sequence identity: Mouse 34%; Rat 31%

Target Information

CD162 (PSGL-1) is a 120 kDa homodimer protein found on the surface of leukocytes and platelets. CD162 is known to bind CD62P (P-selectin), CD62L (L-selectin), and to a lower degree CD62E (E-selectin). These interactions play a critical role in leukocyte adhesion, rolling and extravasation. CD162 has been shown to be an important immune marker of T cell exhaustion in chronic viral infections and cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.