Thermo Fisher Scientific DDX5 Polyclonal Antibody
Human 및 Mouse에 반응하는 DDX5 단클론 항체로 Western blot에 적합. 합성 펩타이드 면역원 사용, 액상 형태로 제공. 0.5 mg/mL 농도, TBS 버퍼에 BSA 및 sodium azide 포함. -20°C에서 보관하며 동결-해동 반복은 피해야 함.
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- PA518260
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (PMIGYPMPTGYSQ) corresponding to the C-terminus amino acids of DDX5 (aa 602–614) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10986453 |
Product Specific Information
- Predicted to react with canine, mouse, and rat based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:2000.
Target Information
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. These proteins are involved in various cellular processes requiring alteration of RNA secondary structure, such as:
- Translation initiation
- Nuclear and mitochondrial splicing
- Ribosome and spliceosome assembly
Some members of this family are associated with embryogenesis, spermatogenesis, and cellular growth and division.
The DDX5 gene encodes a DEAD box protein functioning as an RNA-dependent ATPase and proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen.
This gene consists of 13 exons, and alternatively spliced transcripts containing several intron sequences have been detected, though no isoforms encoded by these transcripts have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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