Thermo Fisher Scientific IPAD Polyclonal Antibody
Shigella flexneri IPAD 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot 및 ELISA에 사용 가능. 단백질 G로 정제된 액상 형태이며, PBS/glycerol buffer에 보관. 세균 단백질 침입 관련 연구용에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bacteria |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Shigella flexneri IPAD protein (1–332 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.819 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3091662 |
Target Information
Required for bacterial invasion of host cells. Controls IpaB and IpaC secretion, and the efficiency with which they are physically inserted into target cell membranes. These proteins are exported via T3SS to form a pore in the host membrane that allows the translocation of other effectors into the host cytoplasm. Along with IpaB, it is essential for both blocking secretion through the Mxi/Spa translocon in the absence of a secretion-inducing signal, and for controlling secretion levels when the signal is present.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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