Thermo Fisher Scientific PGRMC2 Polyclonal Antibody
Thermo Fisher Scientific의 PGRMC2 Polyclonal Antibody는 인간 및 생쥐 시료에 반응하며 WB, ICC/IF, ELISA에 적합합니다. 고순도 친화 크로마토그래피로 정제된 비결합 항체로, 안정적인 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: References
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
- Publications: References
ELISA
- Tested Dilution: 1 µg/mL
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1–50 of human PGRMC2 (NP_0063113) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.89 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855514 |
Product Specific Information
Immunogen sequence:
MAAGDGDVKL GTLGSGSESS NDGGSESPGD AGAAAEGGGW AAAALALLTG
Target Information
PGRMC2 (progesterone receptor membrane component 2), also known as DG6 or PMBP, is a single-pass membrane protein belonging to the cytochrome b5 family (MAPR subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% sequence identity with PGRMC1. Loss of PGRMC2 gene expression is associated with metastasis in uterine endocervical adenocarcinomas, suggesting its role in metastasis suppression.
⚠ WARNING
This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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