Thermo Fisher Scientific Aquaporin 5 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal 항체로 Western blot에 적합. C-말단 영역의 합성 펩타이드 면역원 사용. 항원 친화 크로마토그래피로 정제된 액상 형태. 4°C 단기 보관, -20°C 장기 보관 권장.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- Positive Control: HepG2
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human AQP5 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.47 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2735471 |
Product Specific Information
- Positive Control: HepG2
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed, and it is common for multiple AQP types to be present in the same cell.
Most aquaporins are permeable only to water, but AQP3, AQP7, AQP9, and one AQP10 transcript are also permeable to urea and glycerol.
AQP2 is the only water channel activated by vasopressin to enhance water reabsorption in the kidney collecting duct.
Aquaporins are involved in renal water absorption, pulmonary secretion, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor.
In the lung, AQP5 is responsible for the majority of water transport across the apical membrane of type I alveolar epithelial cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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