Thermo Fisher Scientific IL-6 Recombinant Rabbit Monoclonal Antibody (PS00-21)
Recombinant rabbit monoclonal antibody specific to human IL-6. Validated for ELISA applications. Produced in HEK293 cells, purified via Protein A. Supplied as liquid form in PBS with sodium azide. For research use only.
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Applications
- ELISA (ELISA): Assay-dependent
- Application Notes: Suitable for Sandwich ELISA
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PS00-21 |
| Immunogen | Recombinant full length of human IL-6 protein (amino acids 1–212) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931102 |
Product Specific Information
- Recommended application: Sandwich ELISA
Target Information
Interleukin-6 (IL-6) is a cytokine involved in inflammation and B cell maturation. It acts as an endogenous pyrogen capable of inducing fever in autoimmune or infectious conditions. IL-6 is primarily expressed at sites of acute and chronic inflammation, secreted into serum, and induces transcriptional inflammatory responses via the IL-6 receptor alpha. Dysregulation of IL-6 is associated with multiple inflammatory diseases, including diabetes mellitus, systemic juvenile rheumatoid arthritis, Kaposi sarcoma, and rheumatoid arthritis. Elevated IL-6 levels have also been observed in viral infections such as COVID-19 (SARS-CoV-2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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