
Thermo Fisher Scientific CD13 Recombinant Rabbit Monoclonal Antibody (PD00-39)
Recombinant rabbit monoclonal antibody against human CD13 (clone PD00-39). Validated for IHC (paraffin) at 1:1,000 dilution. Produced in HEK293 cells, purified by Protein A, and supplied as liquid form. Suitable for research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | PD00-39 |
| Immunogen | Synthetic peptide within N-terminal human CD13 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol, 0.1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931108 |
Target Information
CD13 (ANPEP) is a 150–170 kDa type II transmembrane zinc-binding ectopeptidase expressed on various cell types. It acts as a metalloprotease that catalyzes removal of neutral amino acids from small peptides, modulating bioactive peptide activity. CD13 participates in extracellular matrix degradation, antigen processing, and signal transduction. It plays roles in inflammatory responses, intercellular contact, cell motility, and vascularization. CD13 expression is associated with granulocytes, monocytes, and myeloid leukemia cells, contributing to protection against apoptosis and poor prognosis in carcinomas. It also functions as an aminopeptidase enzyme and serves as an alpha receptor for coronavirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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