Thermo Fisher Scientific GAK Monoclonal Antibody (4C10)
Thermo Fisher Scientific의 GAK Monoclonal Antibody (4C10)은 인간 GAK 단백질을 인식하는 mouse IgG1 항체입니다. Western blot, ELISA, Immunoprecipitation에 적합하며, 고순도 affinity chromatography로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.03 ng/mL |
| Immunoprecipitation (IP) | 1–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C10 |
| Immunogen | GAK (AAH08668, 151 a.a. ~ 250 a.a.) partial recombinant protein with GST tag. MW of GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SAVAPTPATE GPLFSPGGQP APCGSQASWT KSQNPDPFAD LGDLSSGLQG SPAGFPPGGF IPKTATTPKG SSSWQTSRPP AQGASWPPQA KPPPKACTQP
Target Information
GAK (Cyclin-G-associated kinase) is a serine/threonine kinase originally identified as a cyclin G-associated protein. Neither CDK5 nor GAK kinase activity is activated by cyclin G, and GAK does not affect CDK5 kinase activity. It functions as an auxilin homolog involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates during the cell cycle, peaking at G1.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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