Thermo Fisher Scientific GAK Monoclonal Antibody (4C10)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

0.03 ng/mL

-

Immunoprecipitation (IP)

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

4C10

Immunogen

GAK (AAH08668, 151 a.a. approximately 250 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GAK,uniProtId:O14976-1,ncbiNodeId:9606,antigenRange:151-250,antigenLength:1311,antigenImageFileName:H00002580-M01_GAK_O14976-1_House_mouse.svg,antigenImageFileNamePDP:H00002580-M01_GAK_O14976-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: SAVAPTPATE GPLFSPGGQP APCGSQASWT KSQNPDPFAD LGDLSSGLQG SPAGFPPGGF IPKTATTPKG SSSWQTSRPP AQGASWPPQA KPPPKACTQP

Target Information

GAK serine/threonine kinase or Cyclin-G-associated kinase was originally identified as a protein that is associated with cyclin G. However, neither CDK5 nor GAK kinase activity is activated by cyclin G nor does GAK affect CDK5 kinase activity. GAK seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.