Thermo Fisher Scientific GALC Monoclonal Antibody (2D1)
GALC 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 2D1). Western blot과 ELISA에 적합하며, 인간 GALC 단백질에 반응. Affinity chromatography로 정제된 액상 형태로, PBS(pH 7.4)에 보존제 없이 제공.
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- H00002581-M01
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Thermo Fisher Scientific GALC Monoclonal Antibody (2D1)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D1 |
| Immunogen | GALC (AAH36518, 27 a.a. approximately 669 a.a) full-length recombinant protein with GST tag. MW of GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
YVLDDSDGLG REFDGIGAVS GGGATSRLLV NYPEPYRSQI LDYLFKPNFG ASLHILKVEI GGDGQTTDGT EPSHMHYALD GNYFRGYEWW LMKEAKKRNP NITLIGLPWS FPGWLGKGFD WPYVNLQLTA YYVVTWIVGA KRYHDLDIDY IGIWNERSYN ANYIKILRKM LNYQGLQRVK IIASDNLWES ISASMLLDAE LFKVVDVIGA HYPGTHSAKD AKLTGKKLWS SEDFSTLNSD MGAGCWGRIL NQNYINGYMT STIAWNLVAS YYEQLPYGRC GLMTAQEPWS GHYVVESPVW VSAHTTQFTQ PGWYYLKTVG HLEKGGSYVA LTDGLGNLTI IIETMSHKHS KCIRPFLPYF NVSQQFATFV LKGSFSEIPE LQVWYTKLGK TSERFLFKQL DSLWLLDSDG SFTLSLHEDE LFTLTTLTTG RKGSYPLPPK SQPFPSTYKD DFNVDYPFFS EAPNFADQTG VFEYFTNIED PGEHHFTLRQ VLNQRPITWA ADASNTISII GDYNWTNLTT KCDVYIETPD TGGVFIAGRV NKGGILIRSA RGIFFWIFAN GSYRVTGDLA GWIIYALGRV EVTAKKWYTL TLTIKGHFAS GMLNDKSLWT DIPVNFPKNG WAAIGTHSFE FAQFDNFRVE ATR
Target Information
This gene encodes a lysosomal protein that hydrolyzes galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride.
Mutations in this gene are associated with Krabbe disease (globoid cell leukodystrophy).
Alternate transcriptional splice variants encoding different isoforms have been characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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