
Thermo Fisher Scientific Lamin A/C Polyclonal Antibody
Lamin A/C 단백질을 검출하기 위한 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot 및 IHC에 적합하며, Human, Mouse, Rat에 반응합니다. 고순도(>95%) 항체로 안정적인 신호 검출이 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminus of Human Lamin A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803417 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
Lamins are intermediate filament proteins forming a matrix on the inner surface of the nuclear envelope. These proteins exist in three forms (A, B, and C) and are found in various cell types. Lamins A and C are alternatively spliced products of the LMNA gene, which is associated with multiple disorders such as:
- Emery-Dreifuss muscular dystrophy
- Dunnigan-type familial partial lipodystrophy (FPLD)
- Limb-girdle muscular dystrophy (LGMD1B)
- Dilated cardiomyopathy (CMD1A)
- Axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1)
- Mandibuloacral dysplasia (MAD)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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